Teneligliptin 20mg Tablet

Tenetin -20 is the brand name for the Teneligliptin 20mg tablet manufactured by Arlak corazon. It is a highly effective oral anti-diabetic medicationmedici is a highly effective oral anti-diabetic medication containing Teneligliptin 20 mg, a potent and selective Dipeptidyl Peptidase-4 (DPP-4) inhibitor. It is designed for the management of Type 2 Diabetes Mellitus (T2DM) and works by improving the body’s natural ability to regulate blood glucose levels.

TENETIN-20 offers long-lasting glycemic control by enhancing insulin secretion and suppressing glucagon release, especially after meals. It helps reduce both fasting plasma glucose (FPG) and postprandial plasma glucose (PPG) levels, ensuring stable blood sugar throughout the day.

This medication is a preferred choice for patients who require effective control of diabetes with minimal risk of hypoglycemia and weight gain.

Mechanism of Action

Teneligliptin belongs to the DPP-4 inhibitor class of oral hypoglycemic agents. Its primary mode of action involves inhibiting the DPP-4 enzyme, which is responsible for breaking down incretin hormones such as Glucagon-like peptide-1 and GIP Glucose-dependent insulinotropic polypeptide.

By preventing the degradation of incretin hormones, Teneligliptin:

• Enhances insulin secretion from pancreatic β-cells in response to meals.
• Suppresses glucagon secretion from α-cells, thereby reducing hepatic glucose output.
• Improves glycemic control without causing significant hypoglycemia.

Indications for Use

TENETIN-20 is indicated for condition such as follows:

• In the Management of Type 2 Diabetes Mellitus (T2DM) in adults.
• As monotherapy when diet and exercise alone do not achieve adequate glycemic control.
• As add-on therapy with other anti-diabetic agents such as Metformin, Sulfonylureas, or Thiazolidinediones when combined therapy is required.
• Patients seeking stable glucose control with low hypoglycemia risk.

Dosage and Administration

tenetin -20 must be used as  prescribed by the doctor self medication or irregular dose can cause unwanted risk or even worsening of the condition. 

• Recommended dose: One tablet of TENETIN-20 once daily.
• Can be taken with or without food.
• Dose adjustments may be required based on blood glucose monitoring and physician guidance.
• Should be used along with proper diet, exercise, and lifestyle modifications for best results.

Possible Side Effects

There are some side effects of this medication which are usually well tolerated and easily adapted by the body but in case it persists contact your doctor immediately. 

• Headache
• Dizziness
• Nausea
• Abdominal discomfort
• Hypoglycemia (rare, usually in combination therapy)
• Mild skin rash or allergic reactions (rare)

Precautions

While using the Tenetin-20, some precaution must be followed to ensure complete and quick recovery such as :  

• Use with caution in patients with renal or hepatic impairment; dose adjustments may be required.
• Not recommended for patients with Type 1 diabetes or diabetic ketoacidosis.
• Pregnant or lactating women should use only under medical supervision.
• Monitor HbA1c and fasting blood glucose levels regularly during treatment.
• Avoid alcohol consumption as it may alter blood sugar levels.
• Should not be combined with medications that may strongly affect glucose metabolism without medical guidance.

 Storage Instructions 

• Keep the medication away from heat and wet/damp places , and store in a cool and dry place.
• Keep it away from direct sunlight
• Keep away from children 
• Must ensure the original packing is not broken before using or storing for a longer time.