Trimetazidine dihydrochloride­ modified release tablet 35mg

Trimetazidine dihydrochloride­ modified release tablet is widely used to treat angina pectoris, a condition marked by chest pain due to reduced blood flow to the heart. This medication is designed in a modified-release formulation, which ensures gradual and controlled release of the drug into the bloodstream. It is an anti-anginal medicine which is used in combination with other medicines to treat angina pectoris. 

Trimetazidine dihydrochloride­ helps the heart work more efficiently by improving how it uses oxygen. This medication prevents new attacks of angina but does not stop an acute attack. It may be classified as a coronary vasodilator, which works by relaxing the smooth muscle of arteries and veins, allowing blood flow to occur more freely. 

Arlak Corazone is an established leader in the pharmaceutical segment, offering a top-quality Trimetazidine dihydrochloride Tablet, marketed under the brand name Coradon MR 35. This tablet should be taken exactly as prescribed by your doctor. 

What is the Mode of Action for Trimetazidine dihydrochloride­ Tablets? 

The working Mechanism of Trimetazidine dihydrochloride­ Tablets has been discussed as follows: 

Trimetazidine dihydrochloride­ Tablets work by inhibiting an enzyme called 3-KAT, which shifts cardiac cell metabolism during ischemia from fatty acid oxidation to the more efficient glucose oxidation. This shift in energy substrate enhances the efficiency of oxygen consumption in heart cells, especially during ischemic episodes, reducing cellular damage and improving overall cardiac performance.

Medical Benefits of Using Trimetazidine dihydrochloride­ Tablets

The tablet helps patients manage their condition and engage in daily activities with less fear of chest pain episodes, ultimately enhancing their quality of life.

A List of Medical Benefits of Using Trimetazidine dihydrochloride­ Tablets is given as follows: 

• This tablet reduces the frequency and severity of angina attacks
• Helps improve exercise tolerance and cardiac function
• Provides supportive therapy for ischemic heart disease
• Along with that, it also protects heart cells from oxidative stress

Possible Side Effects of Using Trimetazidine dihydrochloride­ Tablets

Trimetazidine Tablets can cause side effects ranging from mild to moderate that may differ in every individual. Most of them do not require any medical attention and disappear as the body adjusts to the dose. 

A List of Side Effects has been mentioned as follows: 

• Dizziness
• Headache
• Nausea
• Weakness
• Itching
• Dyspepsia
• Abdominal pain
• Diarrhea

General Safety and Precautions 

A list of safety precautions must be followed while taking Trimetazidine dihydrochloride­ Tablets. Disclose your current or past health conditions to your doctor to avoid any adverse side effects.

Follow the safety measures mentioned below, as follows:  

• It is not recommended for patients with Parkinson’s disease or other movement disorders.
• Do not stop taking this medicine abruptly without consulting your doctor.
• Avoid it if you’re pregnant or breastfeeding. 
• Should be used cautiously in elderly patients
• Avoid taking it if allergic to this medication or any of the other ingredients of this formulation. 

Storage Instructions For Trimetazidine Tablets

Follow the instructions for storing this medication: 

• Store below 30°C in a cool, dry place. 
• Protect the tablets from moisture and light. 
• Keep out of reach of children.
• Do not use after the expiry date mentioned on the pack.

Frequently Asked Questions (FAQ’s)

Q1: How long does it take to show effect?
Relief in angina symptoms is usually seen within a few weeks of consistent use.

Q2: Can I stop the medication suddenly?
No, discontinuation should only be done under medical advice.

Q3: Does it affect blood pressure?
Unlike many other heart medications, Trimetazidine does not alter blood pressure or heart rate.

Q4: What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose