Telmisartan 40mg Hydrochlorothiazide 12.5 mg Tablet

Telmisartan 40mg Hydrochlorothiazide  12.5 mg Tablet contains Telmisartan and Hydrochlorothiazide. It is used for the treatment of hypertension, also termed the condition of high blood pressure.

Telmisartan is an anti-hypertensive drug, act as an angiotensin II receptor antagonist. It inhibits the action of angiotensin II on vascular smooth muscle which reduces arterial blood pressure.

Hydrochlorothiazide is a thiazide diuretic that prevents the body from absorbing salt which causes fluid retention.

Precaution with Telmisartan 40mg Hydrochlorothiazide  12.5 mg Tablets are recommended. Try to maintain a healthy diet, and be in touch with the doctor regularly. Missing the dose may cause ill effects. Combining the medicine with drugs such as anti-biotics, anti-histamines, etc can shoot the blood pressure levels. Take the tablets on time.

People consuming Telmisartan 40mg Hydrochlorothiazide  12.5 mg Tablet regularly may suffer from side effects such as nausea, inflammation in the pancreas, lack of urine formation, and sometimes drowsiness. The tablets are only for external use and do not consume them during pregnancy. 

Indication of Telmisartan 40mg Hydrochlorothiazide  12.5 mg Tablet

• High rate of blood pressure or hypertension. 

Dosage of Telmisartan 40mg Hydrochlorothiazide  12.5 mg Tablet

• The use of tablets should be prescribed by a healthcare professional. You can use the tablets with a glass of water once a day. We recommend you to fix a time for the consumption for possibly the best results. 

Mechanism of action of Telmisartan 40mg Hydrochlorothiazide  12.5 mg Tablet

Telmisartan 40mg Hydrochlorothiazide  12.5 mg Tablet is a combination drug of antihypertensive and diuretic.

• Telmisartan blocks the actions of angiotensin II by binding it to the receptor containing vasoconstrictor and aldosterone-secreting effects. It has greater closeness for AT 2 receptors.
• Hydrochlorothiazide is a thiazide diuretic which acts on renal tubular electrolyte reabsorption. It increases the excretion of sodium and chloride ions.  It also increases the secretion of aldosterone secretion, increases urinary potassium loss, and decreases serum potassium.

Pharmacology of Telmisartan 40mg Hydrochlorothiazide  12.5 mg Tablet

For a better understanding of the product, here is a pharmacology that will describe the effective working of the tablets. 

Telmisartan : Absorption

• After oral administration, the drug is well distributed into the body. The presence of food decreases the bioavailability of the drug.

Distribution of Telmisartan

• The volume of distribution of the drug is 500 L. About 99.5%of the drug is bound to plasma protein. The drug is metabolized by the enzyme cytochrome P 450.

Excretion of Telmisartan

• The drug is excreted in unchanged form in urine and feces.

Hydrochlorothiazide: Absorption

• After oral administration about 50 – 60% of the drug gets absorbed.

Distribution of Hydrochlorothiazide

• About 67.9% of the drug is bound to plasma protein.

Excretion of Hydrochlorothiazide

• The drug follows renal excretion.

Contraindications with Telmisartan 40mg Hydrochlorothiazide  12.5 mg Tablet

Adverse effects of the tablets are very common. For each person, the consumption of anti-hyperactivity tablets will provide different effects. The common obese are mentioned below. 

• Absence of urine formation.
• Acid-base imbalance.
• Abnormal low blood pressure.
• Inflammation of the pancreas.
• Kidney problem.
• Condition of nausea.
• Drowsiness and sometimes a severe headache.

Precautions with Telmisartan 40mg Hydrochlorothiazide  12.5 mg Tablet

The advice precautions with the use of this tablet are described below, Following these will result in the best outcomes. 

• Drugs only to be taken only under the prescription of a physician.
• This is not recommended for pregnant women.
• Patients with increased heart rates, HIV AIDS, liver dysfunctioning, etc must inform the doctor about their medical condition. 
• Allergic to any drug or its combination
• Renal disorder may occur.
• The patient may suffer from Hepatic problem

Note- The Telmisartan 40mg Hydrochlorothiazide  12.5 mg Tablets are only for external use.

Storage- Keep Telmisartan 40mg Hydrochlorothiazide  12.5 mg Tablet in a cool and dry place with no direct context with sunlight.